Synthesis of New 8-Formyl-4-methyl-7-hydroxy Coumarin Derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis and characterization of some new 4-hydroxy-coumarin derivatives.
Some novel coumarins were synthesized starting from 4-hydroxycoumarin and methyl bromoacetate. The structures of the newly obtained compounds were confirmed by elemental analysis, mass, IR and NMR spectra.
متن کاملEfficacy of 4-methyl-7-hydroxy coumarin derivatives against vectors Aedes aegypti and Culex quinquefasciatus.
4-Methyl-7-hydroxy coumarin is considered as a lead molecule as a biopesticide. Its mono bromo and tribromo derivatives were synthesized. Two more derivatives were synthesized by acylation. Compound 1 (3,6,8-tribromo-7-hydroxy-4-methyl-chromen-2-one) was found to be the most potent against IVth instar larvae of C. quinquefasciatus and A. aegypti the LC50 being 1.49 and 2.23 ppm respectively. It...
متن کاملsynthesis of new heterocyclic system n7-ethyl-5-methyl[1,2,4]triazolo[4,3:1,2]pyrimido[4,5d][1,3]thiazol-7-amine & synthesis of novel 7-methyl-3,5-di(alkhylsulfanyl) [1,2,4]triazolo[4,3-c]pyrimidine derivatives
در این تحقیق، ابتدا از واکنش 5-برمو-2-کلرو-6- متیل-4-پیریمیدین آمین (1) با هیدرازین هیدرات در حلال اتانول، 5-برومو-2-هیدرازینو -6-متیل -4-پیریمیدین آمین (2) به دست آمد. سپس از واکنش این ترکیب با تری اتیل اورتو استر های مختلف در حلال استیک اسید محصولات تری آزولوپیریمیدین (a,b3) حاصل گردید. همچنین از واکنش مشتق هیدرازین دار (2) با سدیم نیتریت در حلال استیک اسید و آب حد واسطی ایجاد شده است که از ر...
15 صفحه اولEvaluation of in-vitro antimicrobial activity of some newly synthesized 7-hydroxy 4-methyl coumarin congeners
A series of substituted 8-arylazo 7-hydroxy 4-methyl coumarin (4a-4g) were synthesized and in-vitro evaluation for their preliminary antibacterial activities against E.coli, Staphylococcus aurous, Bacillus subtilis and Pseudomonas aeroginosa were carried out by agar-well diffusion method. Initially, the diazotized primary aryl amines, 3a-3g were synthesized and followed by coupling with 7-hydro...
متن کاملComparative Study of the Synthesis of 7 Hydroxy-4-Methyl Coumarin Mannich Bases by Conventional and Microwave Method
Present work describes the synthesis of coumarin Mannich bases 4-7 by the application of Mannich reaction on 7-hydroxy-4-methyl coumarin 3 using conventional as well as microwave technology to compare the feasibility, reaction time and yield of the product. For this, 7-hydroxy-4-methyl coumarin 3 was prepared using Pechmann condensation reaction and Mannich bases (4-7) were synthesized by the r...
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ژورنال
عنوان ژورنال: Journal of the Korean Chemical Society
سال: 2012
ISSN: 1017-2548
DOI: 10.5012/jkcs.2012.56.4.459